Popular Pizza Spots in Winston-Salem

Christy Bellis

March 21, 2023

Winston-Salem has no shortage of locally owned popular pizza spots to choose from, and each one truly brings its unique take on this classic dish. No matter if you’re looking for a New York-style slice, a gourmet creation, or a classic build-your-own, Winston-Salem has got you covered!

Updated February 2026

Cugino Forno

ADDRESS | 486 N Patterson Ave, Winston-Salem, and 6316 Clemmons Point Dr, Clemmons

Cugino Forno is a family-owned Neapolitan-style pizzeria with locations in Clemmons and downtown Winston-Salem. They wood-fire their traditional-style pizzas in 900-degree ovens sourced directly from Naples.

Pro Tip: At the downtown location, you can pair your pizza with a beer from the brewery next door, Incendiary Brewing.

Elizabeth’s Pizza

ADDRESS | 3278 Silas Creek Pkwy, Winston-Salem, and 2824 University Pkwy, Winston-Salem

Elizabeth’s Pizza has been in business for over thirty years, with multiple locations across the Triad. They offer classic pizza and pasta in a casual space with affordable prices, generous portions, and excellent lunch specials.

Bonus: Gluten-free? No problem — Elizabeth’s has gluten-free crust pizza!

Pizza Greco

ADDRESS | 5089 Country Club Rd, Winston-Salem

The former location of A Slice of Napoli, Pizza Greco is a counter-service, casual-style restaurant serving New York and Sicilian-style pizza. If you’re looking for a pie that can feed a crowd, this is the place to go: they have 24-inch pies!

Bonus: Pizza Greco also has Greek meal options, such as pitas and souvlaki platters.

Tanglewood Pizza Company

ADDRESS | 5539 US-158, Advance

Get ready for imaginative, gourmet wood-fired pizzas in a perfectly sharable size. Tanglewood Pizza Company ramps up the creativity with pizza toppings like pimento cheese, pulled pork, dill pickles, and Brussels sprouts. Gluten-free crust and over twenty-five tap beer options are also on the menu!

Good to Know: Leashed pups are welcome in the covered outdoor patio. Also, musicians frequently perform on the weekends!

Mission Pizza Napoletana

ADDRESS | 707 N Trade St, Winston-Salem

Located in the Arts District downtown, Mission Pizza bakes their Neapolitan-style pizzas in a handmade Stefano Ferraro oven using only the best and freshest locally sourced ingredients. Chef Peyton Smith was named a semifinalist in the category of Best Chef in the Southeast by the James Beard Foundation!

Pro Tip: Book a prix fixe pizza experience at Mission Pizza for a five-course dinner of chef-curated dishes on their website.

Mario’s Pizza

ADDRESS | 2205 Cloverdale Ave NW, Winston-Salem; 1066 Hanes Mall Blvd, Winston-Salem; 266 Harvey St, Winston-Salem; and 1469 River Ridge Dr, Clemmons

Mario’s is a longstanding local pizza chain that came to Winston-Salem in 1998. Co-owned by three Brooklyn natives, Mario’s Pizza is a great spot to grab authentic New York-style pizza.

Pro Tip: Traveling in state? You can enjoy the same delicious New York pizza at their sister restaurant, Tony’s Pizza, with locations in Hickory and Charlotte!

Burke Street Pizza

ADDRESS | 1140 Burke St, Winston-Salem, and 3352 Robinhood Rd, Winston-Salem

You’ll find authentic New York-style slices on the menu at Burke Street Pizza. A Winston-Salem staple since opening in the early 2000s, this pizzeria feels like what you’d find on the corner in New York.

Pro Tip: Affordable, filling lunch specials seven days a week!

Brother’s Pizzeria

ADDRESS | 214 W 4th St, Winston-Salem

Located in the heart of downtown Winston-Salem, Brother’s Pizzeria serves various styles of pizza, such as Jersey, Sicilian, Grandma, and stuffed crust. Italian-American brothers Anthony and Mike Scotto di Frega opened the pizzeria in 2021.

Good to Know: Brother’s Pizzeria is open past midnight on Fridays and Saturdays!

Spaghetti Park

ADDRESS | 3459 Gentry Circle, Clemmons

A quaint to-go spot serving up delicious stone-baked Sicilian pizza. Spaghetti Park’s specialty pies include unique offerings like the Lady and the Goat (goat cheese, shrimp, and peppers) and the Duck It (cranberries, duck, and currant fig-sauce drizzle). The restaurant also serves pasta dishes and entrées.

Bonus: You can get a gluten-free crust for a $3 upcharge, and vegan cheese is available for free!

Grandpa Joe’s Slaberia

ADDRESS | 845 S Poplar St, Winston-Salem

From the team behind Bobby Boy Bakeshop, Grandpa Joe’s serves pizza “slabs” on fresh sourdough focaccia. The toppings range from classics like sausage and pepperoni to unique varieties like mortadella (cured pork sausage) and prosciutto.